These possum/merino/cotton socks are specifically made for those who suffer from diabetes, have had stroke or cardiac issues and struggle with poor circulation. The have a super soft seam, which is barely felt, if at all. Ideally worn for 3-4 weeks at a time, and washed in soft detergent, either by hand or in cool wash cycle. Never dry on direct heat or in tumble dryer. Unique and very high performance sock. Highly recommended.