These possum/merino/cotton socks are specifically made for those who suffer from diabetes, have had stroke or cardiac issues and struggle with poor circulation. They enhance blood flow and help broken skin to heal. They have a super soft seam, which is barely felt, if at all. Ideally worn for 3-4 weeks at a time, and washed in soft detergent, either by hand or in cool wash cycle. Never dry on direct heat or in tumble dryer. Unique and very high performance sock. Highly recommended.